###Gene summary #Tax_id Org_name GeneID status Symbol Functional_stage Aliases Description Other_designations Map_location Chromosome Genomic_nucleotide_accession Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Exon_count OMIM 9606 Homo sapiens 10419 live PRMT5 Proliferation HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs Protein arginine methyltransferase 5,protein arginine N-methyltransferase 5|72 kDa ICln-binding protein|HMT1 hnRNP methyltransferase-like 5|SKB1 homolog|histone-arginine N-methyltransfera 14q11.2 14 NC_000014.9 22920511 22929585 minus 17 604045 ###RefSeq information #SNo. GeneID Symbol Status RNA_nuc_accver CDPpos Prot_accver Genomic_nuc_accver Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Assembly Mature_peptide_accver UniProtKBID PDBID 1 10419 PRMT5 MODEL XM_017020927.1 267..1862 XP_016876416.1 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 2 10419 PRMT5 MODEL XR_001750113.1 - NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 3 10419 PRMT5 MODEL XR_001750114.1 - NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 4 10419 PRMT5 MODEL XR_429287.1 - NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 5 10419 PRMT5 REVIEWED NM_001039619.2 361..2223 NP_001034708.1 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 6 10419 PRMT5 REVIEWED NM_001039619.2 361..2223 NP_001034708.1 NC_018925.2 23388337 23397409 - Alternate CHM1_ - B4DV00 4X63 7 10419 PRMT5 REVIEWED NM_001282953.1 361..2091 NP_001269882.1 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 8 10419 PRMT5 REVIEWED NM_001282953.1 361..2091 NP_001269882.1 NC_018925.2 23388337 23397409 - Alternate CHM1_ - B4DV00 4X63 9 10419 PRMT5 REVIEWED NM_001282954.1 509..2104 NP_001269883.1 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 10 10419 PRMT5 REVIEWED NM_001282954.1 509..2104 NP_001269883.1 NC_018925.2 23388337 23397409 - Alternate CHM1_ - B4DV00 4X63 11 10419 PRMT5 REVIEWED NM_001282955.1 225..2006 NP_001269884.1 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 12 10419 PRMT5 REVIEWED NM_001282955.1 225..2006 NP_001269884.1 NC_018925.2 23388337 23397409 - Alternate CHM1_ - B4DV00 4X63 13 10419 PRMT5 REVIEWED NM_001282956.1 361..1761 NP_001269885.1 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 14 10419 PRMT5 REVIEWED NM_001282956.1 361..1761 NP_001269885.1 NC_018925.2 23388337 23397409 - Alternate CHM1_ - B4DV00 4X63 15 10419 PRMT5 REVIEWED NM_006109.4 225..2138 NP_006100.2 NC_000014.9 22920510 22929584 - Reference GRCh3 - B4DV00 4X63 16 10419 PRMT5 REVIEWED NM_006109.4 225..2138 NP_006100.2 NC_018925.2 23388337 23397409 - Alternate CHM1_ - B4DV00 4X63 ###Gene Ontology #SNo. TaxonID GeneID GOID Evidence Qualifier GOterm PubMedID Category 1 9606 10419 GO:0000387 IMP - spliceosomal snRNP assembly 17709427 Process 2 9606 10419 GO:0000387 TAS - spliceosomal snRNP assembly 0 Process 3 9606 10419 GO:0001046 ISS - core promoter sequence-specific DNA binding 0 Function 4 9606 10419 GO:0003714 ISS - transcription corepressor activity 0 Function 5 9606 10419 GO:0005515 IPI - protein binding 11756452 Function 6 9606 10419 GO:0005634 IDA - nucleus 0 Component 7 9606 10419 GO:0005634 NAS - nucleus 18404153 Component 8 9606 10419 GO:0005654 TAS - nucleoplasm 0 Component 9 9606 10419 GO:0005737 IDA - cytoplasm 22952863 Component 10 9606 10419 GO:0005794 IDA - Golgi apparatus 20421892 Component 11 9606 10419 GO:0005829 IDA - cytosol 18984161 Component 12 9606 10419 GO:0005829 TAS - cytosol 0 Component 13 9606 10419 GO:0006353 IMP - DNA-templated transcription, termination 26700805 Process 14 9606 10419 GO:0006355 IBA - regulation of transcription, DNA-templated 0 Process 15 9606 10419 GO:0007088 TAS - regulation of mitotic nuclear division 9843966 Process 16 9606 10419 GO:0008168 IDA - methyltransferase activity 15369763 Function 17 9606 10419 GO:0008283 TAS - cell proliferation 9843966 Process 18 9606 10419 GO:0008327 IDA - methyl-CpG binding 25284789 Function 19 9606 10419 GO:0008469 TAS - histone-arginine N-methyltransferase activity 0 Function 20 9606 10419 GO:0016274 IDA - protein-arginine N-methyltransferase activity 20421892 Function 21 9606 10419 GO:0016274 TAS - protein-arginine N-methyltransferase activity 0 Function 22 9606 10419 GO:0018216 IMP - peptidyl-arginine methylation 17709427 Process 23 9606 10419 GO:0019918 IEA - peptidyl-arginine methylation, to symmetrical-dimethyl arginine 0 Process 24 9606 10419 GO:0032403 IEA - protein complex binding 0 Function 25 9606 10419 GO:0032922 ISS - circadian regulation of gene expression 0 Process 26 9606 10419 GO:0034709 IDA - methylosome 18984161 Component 27 9606 10419 GO:0035097 IDA - histone methyltransferase complex 23048031 Component 28 9606 10419 GO:0035243 EXP - protein-arginine omega-N symmetric methyltransferase activity 19011621 Function 29 9606 10419 GO:0035243 IMP - protein-arginine omega-N symmetric methyltransferase activity 17709427 Function 30 9606 10419 GO:0035246 IDA - peptidyl-arginine N-methylation 15369763 Process 31 9606 10419 GO:0042118 IMP - endothelial cell activation 22269951 Process 32 9606 10419 GO:0042802 IPI - identical protein binding 11756452 Function 33 9606 10419 GO:0043021 IPI - ribonucleoprotein complex binding 17709427 Function 34 9606 10419 GO:0043234 IEA - protein complex 0 Component 35 9606 10419 GO:0043985 ISS - histone H4-R3 methylation 0 Process 36 9606 10419 GO:0043985 NAS - histone H4-R3 methylation 18404153 Process 37 9606 10419 GO:0044020 IMP - histone methyltransferase activity (H4-R3 specific) 25284789 Function 38 9606 10419 GO:0044030 IEA - regulation of DNA methylation 0 Process 39 9606 10419 GO:0045596 IEA - negative regulation of cell differentiation 0 Process 40 9606 10419 GO:0046982 IDA - protein heterodimerization activity 18495660 Function 41 9606 10419 GO:0048714 IEA - positive regulation of oligodendrocyte differentiation 0 Process 42 9606 10419 GO:0070372 IEA - regulation of ERK1 and ERK2 cascade 0 Process 43 9606 10419 GO:0090161 IMP - Golgi ribbon formation 20421892 Process 44 9606 10419 GO:0097421 IEA - liver regeneration 0 Process 45 9606 10419 GO:1901796 TAS - regulation of signal transduction by p53 class mediator 0 Process 46 9606 10419 GO:1903507 IEA - negative regulation of nucleic acid-templated transcription 0 Process 47 9606 10419 GO:1904992 IGI - positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 26554819 Process