###Gene summary #Tax_id Org_name GeneID status Symbol Functional_stage Aliases Description Other_designations Map_location Chromosome Genomic_nucleotide_accession Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Exon_count OMIM 9606 Homo sapiens 5291 live PIK3CB Proliferation P110BETA, PI3K, PI3KBETA, PIK3C1 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta,phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform|PI3-kinase p110 subunit beta|PI3-kinase subunit beta|PI3K-beta|PtdIns-3- 3q22.3 3 NC_000003.12 138652698 138834938 minus 27 602925 ###RefSeq information #SNo. GeneID Symbol Status RNA_nuc_accver CDPpos Prot_accver Genomic_nuc_accver Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Assembly Mature_peptide_accver UniProtKBID PDBID 1 5291 PIK3CB MODEL XM_005247530.2 366..3578 XP_005247587.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 2 5291 PIK3CB MODEL XM_006713659.3 237..3449 XP_006713722.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 3 5291 PIK3CB MODEL XM_011512895.2 362..3574 XP_011511197.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 4 5291 PIK3CB MODEL XM_011512896.1 135..2843 XP_011511198.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 5 5291 PIK3CB MODEL XM_017006619.1 40..3252 XP_016862108.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 6 5291 PIK3CB MODEL XM_017006620.1 975..2999 XP_016862109.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 7 5291 PIK3CB MODEL XM_017006621.1 975..2948 XP_016862110.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 8 5291 PIK3CB VALIDATED NM_001256045.1 347..2095 NP_001242974.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 9 5291 PIK3CB VALIDATED NM_001256045.1 347..2095 NP_001242974.1 NC_018914.2 138335401 138442206 - Alternate CHM1_ - B4DZI3 - 10 5291 PIK3CB VALIDATED NM_006219.2 17..3229 NP_006210.1 NC_000003.12 138652697 138834937 - Reference GRCh3 - B4DZI3 - 11 5291 PIK3CB VALIDATED NM_006219.2 17..3229 NP_006210.1 NC_018914.2 138335401 138442206 - Alternate CHM1_ - B4DZI3 - ###Gene Ontology #SNo. TaxonID GeneID GOID Evidence Qualifier GOterm PubMedID Category 1 9606 5291 GO:0000187 TAS - activation of MAPK activity 10570282 Process 2 9606 5291 GO:0001935 IEA - endothelial cell proliferation 0 Process 3 9606 5291 GO:0001952 IMP - regulation of cell-matrix adhesion 25139353 Process 4 9606 5291 GO:0002250 IBA - adaptive immune response 0 Process 5 9606 5291 GO:0005515 IPI - protein binding 19380743 Function 6 9606 5291 GO:0005524 IEA - ATP binding 0 Function 7 9606 5291 GO:0005634 IDA - nucleus 0 Component 8 9606 5291 GO:0005730 IDA - nucleolus 0 Component 9 9606 5291 GO:0005737 IBA - cytoplasm 0 Component 10 9606 5291 GO:0005829 TAS - cytosol 0 Component 11 9606 5291 GO:0005886 IBA - plasma membrane 0 Component 12 9606 5291 GO:0005942 IBA - phosphatidylinositol 3-kinase complex 0 Component 13 9606 5291 GO:0006661 TAS - phosphatidylinositol biosynthetic process 0 Process 14 9606 5291 GO:0006874 IEA - cellular calcium ion homeostasis 0 Process 15 9606 5291 GO:0006914 IEA - autophagy 0 Process 16 9606 5291 GO:0006935 TAS - chemotaxis 10570282 Process 17 9606 5291 GO:0006954 IBA - inflammatory response 0 Process 18 9606 5291 GO:0007156 IEA - homophilic cell adhesion via plasma membrane adhesion molecules 0 Process 19 9606 5291 GO:0007165 NAS - signal transduction 10570282 Process 20 9606 5291 GO:0007169 TAS - transmembrane receptor protein tyrosine kinase signaling pathway 21035500 Process 21 9606 5291 GO:0007186 TAS - G-protein coupled receptor signaling pathway 21321382 Process 22 9606 5291 GO:0007411 TAS - axon guidance 0 Process 23 9606 5291 GO:0010508 TAS - positive regulation of autophagy 21321382 Process 24 9606 5291 GO:0010628 IMP - positive regulation of gene expression 25139353 Process 25 9606 5291 GO:0014065 IMP - phosphatidylinositol 3-kinase signaling 25339672 Process 26 9606 5291 GO:0014065 TAS - phosphatidylinositol 3-kinase signaling 21321382 Process 27 9606 5291 GO:0014066 TAS - regulation of phosphatidylinositol 3-kinase signaling 0 Process 28 9606 5291 GO:0016301 IDA - kinase activity 25327288 Function 29 9606 5291 GO:0016303 IBA - 1-phosphatidylinositol-3-kinase activity 0 Function 30 9606 5291 GO:0016303 TAS - 1-phosphatidylinositol-3-kinase activity 0 Function 31 9606 5291 GO:0016310 IDA - phosphorylation 25327288 Process 32 9606 5291 GO:0016477 TAS - cell migration 21035500 Process 33 9606 5291 GO:0030168 TAS - platelet activation 21035500 Process 34 9606 5291 GO:0030496 IDA - midbody 0 Component 35 9606 5291 GO:0033031 IMP - positive regulation of neutrophil apoptotic process 25339672 Process 36 9606 5291 GO:0035004 TAS - phosphatidylinositol 3-kinase activity 21035500 Function 37 9606 5291 GO:0035005 IBA - 1-phosphatidylinositol-4-phosphate 3-kinase activity 0 Function 38 9606 5291 GO:0036092 IEA - phosphatidylinositol-3-phosphate biosynthetic process 0 Process 39 9606 5291 GO:0038095 TAS - Fc-epsilon receptor signaling pathway 0 Process 40 9606 5291 GO:0038096 TAS - Fc-gamma receptor signaling pathway involved in phagocytosis 0 Process 41 9606 5291 GO:0038111 TAS - interleukin-7-mediated signaling pathway 0 Process 42 9606 5291 GO:0040016 IEA - embryonic cleavage 0 Process 43 9606 5291 GO:0043560 IEA - insulin receptor substrate binding 0 Function 44 9606 5291 GO:0045087 IBA - innate immune response 0 Process 45 9606 5291 GO:0046854 IEA - phosphatidylinositol phosphorylation 0 Process 46 9606 5291 GO:0046934 IBA - phosphatidylinositol-4,5-bisphosphate 3-kinase activity 0 Function 47 9606 5291 GO:0046934 TAS - phosphatidylinositol-4,5-bisphosphate 3-kinase activity 0 Function 48 9606 5291 GO:0048010 TAS - vascular endothelial growth factor receptor signaling pathway 0 Process 49 9606 5291 GO:0048015 TAS - phosphatidylinositol-mediated signaling 0 Process 50 9606 5291 GO:0050852 TAS - T cell receptor signaling pathway 0 Process 51 9606 5291 GO:0050900 TAS - leukocyte migration 0 Process 52 9606 5291 GO:0060055 IEA - angiogenesis involved in wound healing 0 Process 53 9606 5291 GO:0060326 IBA - cell chemotaxis 0 Process 54 9606 5291 GO:0070527 TAS - platelet aggregation 21035500 Process 55 9606 5291 GO:2000369 TAS - regulation of clathrin-dependent endocytosis 21321382 Process