###Gene summary #Tax_id Org_name GeneID status Symbol Functional_stage Aliases Description Other_designations Map_location Chromosome Genomic_nucleotide_accession Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Exon_count OMIM 9606 Homo sapiens 6347 live CCL2 Proliferation GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF C-C motif chemokine ligand 2,C-C motif chemokine 2|chemokine (C-C motif) ligand 2|monocyte chemoattractant protein-1|monocyte chemotactic and activating factor|monocyte chemotacti 17q12 17 NC_000017.11 34255277 34257203 plus 3 158105 ###RefSeq information #SNo. GeneID Symbol Status RNA_nuc_accver CDPpos Prot_accver Genomic_nuc_accver Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Assembly Mature_peptide_accver UniProtKBID PDBID 1 6347 CCL2 REVIEWED - - NG_012123.1 5000 6926 + - - P13500 1DOL 2 6347 CCL2 REVIEWED NM_002982.3 74..373 NP_002973.1 NC_000017.11 34255276 34257202 + Reference GRCh3 - P13500 1DOL 3 6347 CCL2 REVIEWED NM_002982.3 74..373 NP_002973.1 NC_018928.2 32646182 32648094 + Alternate CHM1_ - P13500 1DOL 4 6347 CCL2 REVIEWED NM_002982.3 74..373 NP_002973.1 NG_012123.1 5000 6926 + - - P13500 1DOL ###Gene Ontology #SNo. TaxonID GeneID GOID Evidence Qualifier GOterm PubMedID Category 1 9606 6347 GO:0000165 IMP - MAPK cascade 21147091 Process 2 9606 6347 GO:0001525 TAS - angiogenesis 18334747 Process 3 9606 6347 GO:0001666 IEA - response to hypoxia 0 Process 4 9606 6347 GO:0001912 IEA - positive regulation of leukocyte mediated cytotoxicity 0 Process 5 9606 6347 GO:0001938 IEA - positive regulation of endothelial cell proliferation 0 Process 6 9606 6347 GO:0002523 IEA - leukocyte migration involved in inflammatory response 0 Process 7 9606 6347 GO:0002544 IEA - chronic inflammatory response 0 Process 8 9606 6347 GO:0002548 IDA - monocyte chemotaxis 12207323 Process 9 9606 6347 GO:0002693 IEA - positive regulation of cellular extravasation 0 Process 10 9606 6347 GO:0004672 TAS - protein kinase activity 9973507 Function 11 9606 6347 GO:0005102 TAS - receptor binding 10542238 Function 12 9606 6347 GO:0005515 IPI - protein binding 26095031 Function 13 9606 6347 GO:0005576 IDA - extracellular region 20041150 Component 14 9606 6347 GO:0005576 TAS - extracellular region 0 Component 15 9606 6347 GO:0005615 IBA - extracellular space 0 Component 16 9606 6347 GO:0005791 IEA - rough endoplasmic reticulum 0 Component 17 9606 6347 GO:0006468 TAS - protein phosphorylation 9670957 Process 18 9606 6347 GO:0006874 IEA - cellular calcium ion homeostasis 0 Process 19 9606 6347 GO:0006935 TAS - chemotaxis 10623817 Process 20 9606 6347 GO:0006954 IDA - inflammatory response 21147091 Process 21 9606 6347 GO:0006959 TAS - humoral immune response 9548499 Process 22 9606 6347 GO:0007010 IDA - cytoskeleton organization 10072545 Process 23 9606 6347 GO:0007155 TAS - cell adhesion 10198043 Process 24 9606 6347 GO:0007165 NAS - signal transduction 10770925 Process 25 9606 6347 GO:0007166 TAS - cell surface receptor signaling pathway 9548499 Process 26 9606 6347 GO:0007179 IEA - transforming growth factor beta receptor signaling pathway 0 Process 27 9606 6347 GO:0007186 TAS - G-protein coupled receptor signaling pathway 10542238 Process 28 9606 6347 GO:0007187 TAS - G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 10770925 Process 29 9606 6347 GO:0007259 TAS - JAK-STAT cascade 9670957 Process 30 9606 6347 GO:0007568 IEA - aging 0 Process 31 9606 6347 GO:0008009 IBA - chemokine activity 0 Function 32 9606 6347 GO:0008201 IEA - heparin binding 0 Function 33 9606 6347 GO:0008360 IDA - regulation of cell shape 10072545 Process 34 9606 6347 GO:0009408 IEA - response to heat 0 Process 35 9606 6347 GO:0009611 IEA - response to wounding 0 Process 36 9606 6347 GO:0009612 IEA - response to mechanical stimulus 0 Process 37 9606 6347 GO:0009617 NAS - response to bacterium 16034137 Process 38 9606 6347 GO:0009887 TAS - animal organ morphogenesis 9364936 Process 39 9606 6347 GO:0010332 IEA - response to gamma radiation 0 Process 40 9606 6347 GO:0010469 IEA - regulation of receptor activity 0 Process 41 9606 6347 GO:0010574 IEA - regulation of vascular endothelial growth factor production 0 Process 42 9606 6347 GO:0010759 IEA - positive regulation of macrophage chemotaxis 0 Process 43 9606 6347 GO:0014823 IEA - response to activity 0 Process 44 9606 6347 GO:0016525 IEA - negative regulation of angiogenesis 0 Process 45 9606 6347 GO:0019079 TAS - viral genome replication 10985244 Process 46 9606 6347 GO:0019221 IDA - cytokine-mediated signaling pathway 12207323 Process 47 9606 6347 GO:0019725 TAS - cellular homeostasis 18334747 Process 48 9606 6347 GO:0030139 IEA - endocytic vesicle 0 Component 49 9606 6347 GO:0030425 IEA - dendrite 0 Component 50 9606 6347 GO:0030593 IBA - neutrophil chemotaxis 0 Process 51 9606 6347 GO:0031100 IEA - animal organ regeneration 0 Process 52 9606 6347 GO:0031663 IDA - lipopolysaccharide-mediated signaling pathway 21147091 Process 53 9606 6347 GO:0031727 ISS - CCR2 chemokine receptor binding 0 Function 54 9606 6347 GO:0031727 TAS - CCR2 chemokine receptor binding 18021937 Function 55 9606 6347 GO:0032570 IEA - response to progesterone 0 Process 56 9606 6347 GO:0032760 IEA - positive regulation of tumor necrosis factor production 0 Process 57 9606 6347 GO:0032869 IEA - cellular response to insulin stimulus 0 Process 58 9606 6347 GO:0032967 IEA - positive regulation of collagen biosynthetic process 0 Process 59 9606 6347 GO:0033552 IEA - response to vitamin B3 0 Process 60 9606 6347 GO:0034351 IDA - negative regulation of glial cell apoptotic process 12753088 Process 61 9606 6347 GO:0035684 ISS - helper T cell extravasation 0 Process 62 9606 6347 GO:0035690 IEA - cellular response to drug 0 Process 63 9606 6347 GO:0036006 IEA - cellular response to macrophage colony-stimulating factor stimulus 0 Process 64 9606 6347 GO:0036120 IEA - cellular response to platelet-derived growth factor stimulus 0 Process 65 9606 6347 GO:0036499 TAS - PERK-mediated unfolded protein response 0 Process 66 9606 6347 GO:0043200 IEA - response to amino acid 0 Process 67 9606 6347 GO:0043204 IEA - perikaryon 0 Component 68 9606 6347 GO:0043491 IMP - protein kinase B signaling 21147091 Process 69 9606 6347 GO:0043524 IDA - negative regulation of neuron apoptotic process 12753088 Process 70 9606 6347 GO:0043547 IBA - positive regulation of GTPase activity 0 Process 71 9606 6347 GO:0043615 IDA - astrocyte cell migration 12271471 Process 72 9606 6347 GO:0043679 IEA - axon terminus 0 Component 73 9606 6347 GO:0044299 IEA - C-fiber 0 Component 74 9606 6347 GO:0044344 IEP - cellular response to fibroblast growth factor stimulus 9407497 Process 75 9606 6347 GO:0045471 IEA - response to ethanol 0 Process 76 9606 6347 GO:0046677 IEA - response to antibiotic 0 Process 77 9606 6347 GO:0048010 IEA - vascular endothelial growth factor receptor signaling pathway 0 Process 78 9606 6347 GO:0048246 IDA - macrophage chemotaxis 12207323 Process 79 9606 6347 GO:0048247 IEA - lymphocyte chemotaxis 0 Process 80 9606 6347 GO:0048471 IEA - perinuclear region of cytoplasm 0 Component 81 9606 6347 GO:0050806 IEA - positive regulation of synaptic transmission 0 Process 82 9606 6347 GO:0050870 ISS - positive regulation of T cell activation 0 Process 83 9606 6347 GO:0051770 ISS - positive regulation of nitric-oxide synthase biosynthetic process 0 Process 84 9606 6347 GO:0060135 IEA - maternal process involved in female pregnancy 0 Process 85 9606 6347 GO:0060137 IEA - maternal process involved in parturition 0 Process 86 9606 6347 GO:0070098 IBA - chemokine-mediated signaling pathway 0 Process 87 9606 6347 GO:0070374 IBA - positive regulation of ERK1 and ERK2 cascade 0 Process 88 9606 6347 GO:0071222 ISS - cellular response to lipopolysaccharide 0 Process 89 9606 6347 GO:0071300 IEA - cellular response to retinoic acid 0 Process 90 9606 6347 GO:0071318 IEA - cellular response to ATP 0 Process 91 9606 6347 GO:0071333 IEA - cellular response to glucose stimulus 0 Process 92 9606 6347 GO:0071346 IEP - cellular response to interferon-gamma 9407497 Process 93 9606 6347 GO:0071346 ISS - cellular response to interferon-gamma 0 Process 94 9606 6347 GO:0071347 IEP - cellular response to interleukin-1 9407497 Process 95 9606 6347 GO:0071347 ISS - cellular response to interleukin-1 0 Process 96 9606 6347 GO:0071354 IEA - cellular response to interleukin-6 0 Process 97 9606 6347 GO:0071356 IEP - cellular response to tumor necrosis factor 9407497 Process 98 9606 6347 GO:0071356 ISS - cellular response to tumor necrosis factor 0 Process 99 9606 6347 GO:0071392 IEA - cellular response to estradiol stimulus 0 Process 100 9606 6347 GO:0071398 IEA - cellular response to fatty acid 0 Process 101 9606 6347 GO:0071403 IEA - cellular response to high density lipoprotein particle stimulus 0 Process 102 9606 6347 GO:0071407 IDA - cellular response to organic cyclic compound 21147091 Process 103 9606 6347 GO:0071549 IEA - cellular response to dexamethasone stimulus 0 Process 104 9606 6347 GO:0090026 IEA - positive regulation of monocyte chemotaxis 0 Process 105 9606 6347 GO:0090265 IEA - positive regulation of immune complex clearance by monocytes and macrophages 0 Process 106 9606 6347 GO:0090280 IDA - positive regulation of calcium ion import 10925302 Process 107 9606 6347 GO:0090303 IEA - positive regulation of wound healing 0 Process 108 9606 6347 GO:0090314 IEA - positive regulation of protein targeting to membrane 0 Process 109 9606 6347 GO:1905237 IEA - response to cyclosporin A 0 Process 110 9606 6347 GO:2000427 ISS - positive regulation of apoptotic cell clearance 0 Process 111 9606 6347 GO:2000502 IDA - negative regulation of natural killer cell chemotaxis 7545673 Process