###Gene summary #Tax_id Org_name GeneID status Symbol Functional_stage Aliases Description Other_designations Map_location Chromosome Genomic_nucleotide_accession Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Exon_count OMIM 9606 Homo sapiens 6348 live CCL3 Proliferation G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 C-C motif chemokine ligand 3,C-C motif chemokine 3|G0/G1 switch regulatory protein 19-1|PAT 464.1|SIS-beta|chemokine (C-C motif) ligand 3|macrophage inflammatory protein 1-alpha|s 17q12 17 NC_000017.11 36088256 36090160 minus 3 182283 ###RefSeq information #SNo. GeneID Symbol Status RNA_nuc_accver CDPpos Prot_accver Genomic_nuc_accver Start_pos_on_genomic_acc End_pos_on_genomic_acc Orientation Assembly Mature_peptide_accver UniProtKBID PDBID 1 6348 CCL3 REVIEWED - - NG_027730.1 5000 6904 + - - P10147 1B53 2 6348 CCL3 REVIEWED NM_002983.2 103..381 NP_002974.1 NC_000017.11 36088255 36090159 - Reference GRCh3 - P10147 1B53 3 6348 CCL3 REVIEWED NM_002983.2 103..381 NP_002974.1 NC_018928.2 34479826 34481730 - Alternate CHM1_ - P10147 1B53 4 6348 CCL3 REVIEWED NM_002983.2 103..381 NP_002974.1 NG_027730.1 5000 6904 + - - P10147 1B53 5 6348 CCL3 REVIEWED NM_002983.2 103..381 NP_002974.1 NT_187614.1 323129 325033 - Reference GRCh3 - P10147 1B53 6 6348 CCL3 REVIEWED NM_002983.2 103..381 NP_002974.1 NT_187661.1 42352 44256 - Reference GRCh3 - P10147 1B53 ###Gene Ontology #SNo. TaxonID GeneID GOID Evidence Qualifier GOterm PubMedID Category 1 9606 6348 GO:0000165 IEP - MAPK cascade 12032188 Process 2 9606 6348 GO:0000165 IMP - MAPK cascade 21147091 Process 3 9606 6348 GO:0001649 IEP - osteoblast differentiation 21403648 Process 4 9606 6348 GO:0001775 IDA - cell activation 10706735 Process 5 9606 6348 GO:0002548 IC - monocyte chemotaxis 10660125 Process 6 9606 6348 GO:0002548 IDA - monocyte chemotaxis 10706735 Process 7 9606 6348 GO:0004672 IDA - protein kinase activity 10734056 Function 8 9606 6348 GO:0004698 IDA - calcium-dependent protein kinase C activity 15764707 Function 9 9606 6348 GO:0005515 IPI - protein binding 20959807 Function 10 9606 6348 GO:0005576 IDA - extracellular region 20041150 Component 11 9606 6348 GO:0005576 TAS - extracellular region 0 Component 12 9606 6348 GO:0005615 IDA - extracellular space 20167378 Component 13 9606 6348 GO:0005622 IDA - intracellular 10072545 Component 14 9606 6348 GO:0005737 IDA - cytoplasm 21784977 Component 15 9606 6348 GO:0005829 IDA - cytosol 19523456 Component 16 9606 6348 GO:0006816 IDA - calcium ion transport 10734056 Process 17 9606 6348 GO:0006874 IDA - cellular calcium ion homeostasis 10072545 Process 18 9606 6348 GO:0006887 IDA - exocytosis 10734056 Process 19 9606 6348 GO:0006935 IDA - chemotaxis 10679098 Process 20 9606 6348 GO:0006954 IDA - inflammatory response 10679098 Process 21 9606 6348 GO:0007010 IDA - cytoskeleton organization 10072545 Process 22 9606 6348 GO:0007186 IBA - G-protein coupled receptor signaling pathway 0 Process 23 9606 6348 GO:0007267 IDA - cell-cell signaling 10679098 Process 24 9606 6348 GO:0007610 IDA - behavior 20167378 Process 25 9606 6348 GO:0008009 IDA - chemokine activity 10072545 Function 26 9606 6348 GO:0008360 IDA - regulation of cell shape 10072545 Process 27 9606 6348 GO:0009636 IDA - response to toxic substance 10841574 Process 28 9606 6348 GO:0010469 IEA - regulation of receptor activity 0 Process 29 9606 6348 GO:0010628 IDA - positive regulation of gene expression 10706735 Process 30 9606 6348 GO:0010629 IDA - negative regulation of gene expression 21403648 Process 31 9606 6348 GO:0010818 IDA - T cell chemotaxis 10706735 Process 32 9606 6348 GO:0014808 IDA - release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 19523456 Process 33 9606 6348 GO:0016004 IDA - phospholipase activator activity 10734056 Function 34 9606 6348 GO:0016301 IDA - kinase activity 21403648 Function 35 9606 6348 GO:0019722 IDA - calcium-mediated signaling 10072545 Process 36 9606 6348 GO:0023052 IEP - signaling 12032188 Process 37 9606 6348 GO:0030335 IDA - positive regulation of cell migration 7545673 Process 38 9606 6348 GO:0030502 IDA - negative regulation of bone mineralization 21403648 Process 39 9606 6348 GO:0030593 IDA - neutrophil chemotaxis 10706735 Process 40 9606 6348 GO:0031663 IDA - lipopolysaccharide-mediated signaling pathway 21147091 Process 41 9606 6348 GO:0031726 IPI - CCR1 chemokine receptor binding 7545673 Function 42 9606 6348 GO:0031730 IPI - CCR5 chemokine receptor binding 8699119 Function 43 9606 6348 GO:0032760 ISS - positive regulation of tumor necrosis factor production 0 Process 44 9606 6348 GO:0042056 IDA - chemoattractant activity 10072545 Function 45 9606 6348 GO:0042802 IPI - identical protein binding 20959807 Function 46 9606 6348 GO:0043308 IDA - eosinophil degranulation 10706735 Process 47 9606 6348 GO:0043491 IMP - protein kinase B signaling 21147091 Process 48 9606 6348 GO:0043525 ISS - positive regulation of neuron apoptotic process 0 Process 49 9606 6348 GO:0043547 IBA - positive regulation of GTPase activity 0 Process 50 9606 6348 GO:0043615 ISS - astrocyte cell migration 0 Process 51 9606 6348 GO:0043922 IDA - negative regulation by host of viral transcription 10841574 Process 52 9606 6348 GO:0045671 IDA - negative regulation of osteoclast differentiation 21403648 Process 53 9606 6348 GO:0048245 IDA - eosinophil chemotaxis 10072545 Process 54 9606 6348 GO:0048246 ISS - macrophage chemotaxis 0 Process 55 9606 6348 GO:0048247 IDA - lymphocyte chemotaxis 10706735 Process 56 9606 6348 GO:0050718 ISS - positive regulation of interleukin-1 beta secretion 0 Process 57 9606 6348 GO:0050729 ISS - positive regulation of inflammatory response 0 Process 58 9606 6348 GO:0050850 IMP - positive regulation of calcium-mediated signaling 10679098 Process 59 9606 6348 GO:0050918 IEA - positive chemotaxis 0 Process 60 9606 6348 GO:0051897 IEP - positive regulation of protein kinase B signaling 21403648 Process 61 9606 6348 GO:0051928 IDA - positive regulation of calcium ion transport 8699119 Process 62 9606 6348 GO:0051930 IDA - regulation of sensory perception of pain 15764707 Process 63 9606 6348 GO:0070098 IBA - chemokine-mediated signaling pathway 0 Process 64 9606 6348 GO:0070374 IDA - positive regulation of ERK1 and ERK2 cascade 21403648 Process 65 9606 6348 GO:0070723 IDA - response to cholesterol 19523456 Process 66 9606 6348 GO:0071346 IEP - cellular response to interferon-gamma 9407497 Process 67 9606 6348 GO:0071347 IEP - cellular response to interleukin-1 9407497 Process 68 9606 6348 GO:0071356 IEP - cellular response to tumor necrosis factor 9407497 Process 69 9606 6348 GO:0071407 IDA - cellular response to organic cyclic compound 21147091 Process 70 9606 6348 GO:0071621 IDA - granulocyte chemotaxis 10706735 Process 71 9606 6348 GO:0090280 TAS - positive regulation of calcium ion import 10925302 Process 72 9606 6348 GO:2000503 IDA - positive regulation of natural killer cell chemotaxis 7545673 Process