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LIF, interleukin 6 family cytokine gene (Gene Id: 3976  Symbol: LIF) in Homo sapiens

Functional stage: Proliferation

Refseq information: 6

SNo.	Status	RNA nucleotide accession	Protein accession	Genomic nucleotide accession	Start position on genomic DNA	End position on genomic DNA	Orientation	Assembly	Symbol	UniProtkb ID	PDB ID
1	REVIEWED	-	-	NG_008721.1	4956	11360	+	-	LIF	P15018	2Q7N
2	REVIEWED	NM_001257135.1	NP_001244064.1	NC_000022.11	30240446	30246850	-	Reference GRCh3	LIF	P15018	2Q7N
3	REVIEWED	NM_001257135.1	NP_001244064.1	NC_018933.2	30595572	30601976	-	Alternate CHM1_	LIF	P15018	2Q7N
4	REVIEWED	NM_002309.4	NP_002300.1	NC_000022.11	30240446	30246850	-	Reference GRCh3	LIF	P15018	2Q7N
5	REVIEWED	NM_002309.4	NP_002300.1	NC_018933.2	30595572	30601976	-	Alternate CHM1_	LIF	P15018	2Q7N
6	REVIEWED	NM_002309.4	NP_002300.1	NG_008721.1	4956	11360	+	-	LIF	P15018	2Q7N

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Pubmed links

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GO Term: 45
SNo.	Reported in speceis	Evidence	Qualifier	GO term	Category	Pubmed Link
1	Homo sapiens	IDA	-	transcription factor activity, RNA polymerase II transcription factor recruiting	Function	22783022
2	Homo sapiens	IEA	-	blood vessel remodeling	Process	No
3	Homo sapiens	IPI	-	receptor binding	Function	8999038
4	Homo sapiens	IDA	-	cytokine activity	Function	7957045
5	Homo sapiens	IDA	-	leukemia inhibitory factor receptor binding	Function	7957045
6	Homo sapiens	IPI	-	leukemia inhibitory factor receptor binding	Function	8999038
7	Homo sapiens	IPI	-	protein binding	Function	14527405
8	Homo sapiens	TAS	-	extracellular region	Component	No
9	Homo sapiens	IC	-	extracellular space	Component	12643274
10	Homo sapiens	IDA	-	cytosol	Component	No
11	Homo sapiens	IEA	-	immune response	Process	No
12	Homo sapiens	IEA	-	tyrosine phosphorylation of STAT protein	Process	No
13	Homo sapiens	TAS	-	multicellular organism development	Process	3143918
14	Homo sapiens	IEA	-	embryo implantation	Process	No
15	Homo sapiens	IDA	-	growth factor activity	Function	7957045
16	Homo sapiens	IDA	-	positive regulation of cell proliferation	Process	7957045
17	Homo sapiens	IEA	-	negative regulation of cell proliferation	Process	No
18	Homo sapiens	IEA	-	regulation of receptor activity	Process	No
19	Homo sapiens	IEA	-	stem cell population maintenance	Process	No
20	Homo sapiens	IDA	-	positive regulation of peptidyl-serine phosphorylation	Process	7508917
21	Homo sapiens	IDA	-	positive regulation of peptidyl-serine phosphorylation of STAT protein	Process	20624457
22	Homo sapiens	IDA	-	positive regulation of tyrosine phosphorylation of STAT protein	Process	20624457
23	Homo sapiens	IDA	-	positive regulation of MAPK cascade	Process	7508917
24	Homo sapiens	IDA	-	positive regulation of macrophage differentiation	Process	7957045
25	Homo sapiens	IEA	-	negative regulation of meiotic nuclear division	Process	No
26	Homo sapiens	IDA	-	positive regulation of transcription from RNA polymerase II promoter	Process	7508917
27	Homo sapiens	IEA	-	decidualization	Process	No
28	Homo sapiens	IDA	-	negative regulation of hormone secretion	Process	7867561
29	Homo sapiens	IEA	-	lung alveolus development	Process	No
30	Homo sapiens	IEA	-	muscle organ morphogenesis	Process	No
31	Homo sapiens	IEA	-	neuron development	Process	No
32	Homo sapiens	IEA	-	positive regulation of astrocyte differentiation	Process	No
33	Homo sapiens	IDA	-	leukemia inhibitory factor signaling pathway	Process	8999038
34	Homo sapiens	IEA	-	stem cell differentiation	Process	No
35	Homo sapiens	IDA	-	positive regulation of peptidyl-tyrosine phosphorylation	Process	7508917
36	Homo sapiens	IEA	-	lung vasculature development	Process	No
37	Homo sapiens	IEA	-	lung lobe morphogenesis	Process	No
38	Homo sapiens	IEA	-	trophoblast giant cell differentiation	Process	No
39	Homo sapiens	IEA	-	spongiotrophoblast differentiation	Process	No
40	Homo sapiens	IEA	-	negative regulation of ERK1 and ERK2 cascade	Process	No
41	Homo sapiens	IDA	-	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Process	20624457
42	Homo sapiens	IDA	-	regulation of metanephric nephron tubule epithelial cell differentiation	Process	20624457
43	Homo sapiens	IDA	-	positive regulation of protein localization to nucleus	Process	22783022
44	Homo sapiens	IDA	-	positive regulation of histone H3-K27 acetylation	Process	22783022
45	Homo sapiens	IEA	-	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Process	No